The James F. Byrnes High School Bands has long been a source of pride for the community, and an ambassador for the District Five Schools of Spartanburg County. The band program has established a long tradition of excellence in musical performance, and student leadership. The James F. Byrnes band boasts one of the most comprehensive band programs, and one of the finest Performing Fine Arts Centers in South Carolina with nearly 400 students participating in several band or guard performing ensembles at James F. Byrnes High School annually.

The James F. Byrnes High School band program consists of 4 concert ensembles, 2 marching bands, 3 winter guards, and several chamber ensembles. The James F. Byrnes Band Program is fortunate to have state of the art facilities such as the Spartanburg School District Five Fine Arts Center.